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C-SURP Spotlight: Joseph Szydlo, Queens College

January 22, 2014 | Announcements, News, Research, Student Resources

Joseph Szydlo is a rising senior psychology major at Queens College. In the summer of 2012 Joseph worked in the Rutgers University Biomedical Engineering laboratory. That experience provided him with his first entry into the world of laboratory-based experimentation, and whetted his appetite for another hands-on intensive research experience at CUNY. Joseph worked in Dr. Joshua Brumberg’s Laboratory of Cortical Circuitry at Queens College this summer. 

Dr. Joshua Brumberg (left) mentored Joseph Szydlo (right).  Joseph’s research project was titled The Effect of Sensory Deprivation on M1 and M2 Microglia in the Barrel Cortex of Mice.

Dr. Joshua Brumberg (left) mentored Joseph Szydlo (right). Joseph’s research project was titled The Effect of Sensory Deprivation on M1 and M2 Microglia in the Barrel Cortex of Mice.

Joseph’s study aimed to investigate how sensory deprivation achieved by trimming the whiskers of mice, would affect the shape, size and overall cell density of microglia within the sensory cortex of mouse brains. Microglia are the resident macrophages—cells that ingest foreign particles, bacteria, or cell debris—of the central nervous system and serve as the primary immune defense in the brain. 

Interestingly, Joseph worked in the lab with Racheli Wercberger, a 2012 C-SURP participant, who also continued to work with Dr. Brumberg, and used this research experience to write her senior thesis. Racheli is now pursuing her doctorate in neuroscience at the University of California San Francisco. Dr. Brumberg plans to co-author a paper with his two C-SURP students based on the findings from this project.